Che-Hsin Lee Selected Research

beta-thujaplicin

1/2022	Hinokitiol impedes tumor drug resistance by suppressing protein kinase B/mammalian targets of rapamycin axis.
1/2020	Hinokitiol reduces tumor metastasis by inhibiting heparanase via extracellular signal-regulated kinase and protein kinase B pathway.
9/2017	Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells.
4/2016	Hinokitiol inhibits vasculogenic mimicry activity of breast cancer stem/progenitor cells through proteasome-mediated degradation of epidermal growth factor receptor.
2/2016	Hinokitiol Inhibits Melanogenesis via AKT/mTOR Signaling in B16F10 Mouse Melanoma Cells.
1/2016	Hinokitiol induces autophagy in murine breast and colorectal cancer cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Che-Hsin Lee Research Topics

Disease

47	Neoplasms (Cancer) 01/2022 - 01/2003
12	Inflammation (Inflammations) 09/2017 - 10/2010
9	Neoplasm Metastasis (Metastasis) 06/2021 - 05/2010
7	Melanoma (Melanoma, Malignant) 01/2021 - 10/2012
5	Hepatocellular Carcinoma (Hepatoma) 02/2020 - 01/2003
4	Breast Neoplasms (Breast Cancer) 09/2017 - 06/2012
4	Osteoarthritis 10/2013 - 02/2009
3	COVID-19 07/2021 - 01/2021
3	Infections 02/2020 - 10/2010
3	Hypoxia (Hypoxemia) 04/2014 - 02/2005
2	Hyperpigmentation 01/2019 - 02/2016
2	Colorectal Neoplasms (Colorectal Cancer) 01/2016 - 01/2015
2	Colitis 11/2013 - 11/2012
2	Disease Progression 10/2013 - 02/2009
2	Lung Neoplasms (Lung Cancer) 08/2012 - 05/2010
2	Experimental Arthritis 02/2011 - 11/2009
2	Arthritis (Polyarthritis) 02/2011 - 06/2008
1	Esophageal Squamous Cell Carcinoma 12/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2021
1	Acne Vulgaris 01/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Fibrosis (Cirrhosis) 02/2020
1	Liver Cirrhosis (Hepatic Cirrhosis) 02/2020
1	Liver Diseases (Liver Disease) 02/2020

Drug/Important Bio-Agent (IBA)

11	Antineoplastic Agents (Antineoplastics)IBA 06/2021 - 12/2004
10	Therapeutic UsesIBA 01/2022 - 10/2010
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2017
8	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 05/2005
6	beta-thujaplicinIBA 01/2022 - 01/2016
6	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2022 - 01/2016
6	CytokinesIBA 10/2021 - 01/2010
5	Sirolimus (Rapamycin)FDA Link 01/2022 - 01/2016
5	Connexin 43 (Connexin43)IBA 01/2019 - 10/2013
4	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 01/2022 - 01/2016
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2016 - 12/2004
3	KynurenineIBA 01/2018 - 02/2011
3	ResveratrolIBA 01/2017 - 10/2012
2	Fluorouracil (Carac)FDA LinkGeneric 01/2022 - 01/2018
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2022 - 01/2018
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2021 - 07/2021
2	HMGB1 Protein (HMG1)IBA 06/2021 - 01/2016
2	heparanaseIBA 01/2021 - 01/2020
2	ChemokinesIBA 01/2021 - 02/2008
2	hepatitis B virus X proteinIBA 02/2020 - 01/2003
2	ConnexinsIBA 01/2019 - 07/2015
2	EnzymesIBA 01/2019 - 01/2016
2	Eicosapentaenoic AcidIBA 01/2018 - 06/2014
2	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2018 - 02/2011
2	polyallylamineIBA 05/2017 - 02/2013
2	Tryptophan (L-Tryptophan)FDA Link 01/2017 - 01/2016
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 01/2010
2	Epidermal Growth Factor (EGF)IBA 01/2016 - 09/2014
2	Small Interfering RNA (siRNA)IBA 01/2016 - 10/2013
2	AntioxidantsIBA 01/2016 - 01/2014
2	Transcription Factors (Transcription Factor)IBA 12/2014 - 01/2007
2	Aldehyde DehydrogenaseIBA 09/2014 - 06/2012
2	Dextrans (Dextran)FDA Link 11/2013 - 11/2012
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 11/2013 - 11/2012
2	LuciferasesIBA 10/2012 - 01/2007
2	Biological ProductsIBA 08/2012 - 01/2012
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 06/2012 - 01/2010
2	Toll-Like Receptor 4IBA 05/2012 - 01/2010
2	Thrombospondin 1IBA 10/2010 - 02/2005
2	kallistatinIBA 05/2010 - 02/2009
1	DNA VaccinesIBA 10/2021
1	Fluorine-18IBA 07/2021
1	TOR Serine-Threonine KinasesIBA 06/2021
1	Interleukin-1beta (Interleukin 1 beta)IBA 06/2021
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2021
1	Serum AlbuminIBA 03/2021
1	ChloridesIBA 03/2021
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 03/2021
1	SodiumIBA 03/2021
1	GABA Plasma Membrane Transport ProteinsIBA 03/2021
1	Excitatory Amino Acid Transporter 2IBA 03/2021
1	Superoxide Dismutase-1IBA 03/2021
1	rho Guanine Nucleotide Dissociation Inhibitor alphaIBA 03/2021
1	TransferasesIBA 03/2021
1	limbic system-associated membrane proteinIBA 03/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 02/2021
1	Antiviral Agents (Antivirals)IBA 02/2021
1	Chloroquine (Aralen)FDA LinkGeneric 02/2021
1	Chemokine CXCL12IBA 01/2021
1	CXC ChemokinesIBA 01/2021
1	LigandsIBA 01/2021
1	Bone Morphogenetic Protein 5IBA 02/2020
1	AntigensIBA 02/2020
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2020
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2020
1	Apoptosis Regulatory ProteinsIBA 01/2020
1	B7-H1 AntigenIBA 12/2019
1	Immune Checkpoint ProteinsIBA 12/2019

Therapy/Procedure

21	Therapeutics 10/2021 - 01/2003
8	Drug Therapy (Chemotherapy) 01/2022 - 01/2012
6	Immunotherapy 10/2021 - 01/2016
2	Aftercare (After-Treatment) 02/2021 - 01/2007
1	Immunomodulation 10/2021
1	Personal Protective Equipment 01/2021
1	Skin Care 01/2021
1	Complementary Therapies (Alternative Medicine) 01/2020